Cardiotoxicity is a well-established complication of oncology therapies.Cardiomyopathy resulting from anthracyclines is a classic example.In the past decade, an explosion of novel cancer therapies, often targeted and more specific than conventional therapies, has revolutionized 53-264817 oncology therapy and dramatically changed cancer prognosis.Ho
Abstract Introduction Amyotrophic lateral sclerosis (the most common form 53-264817 of motor neuron disease) is a progressive and devastating disease involving both lower and upper motor neurons, typically following a relentless path towards death.Given the gravity of this diagnosis, all efforts must be made by the clinician to exclude alternative
Carica papaya is a well-known plant with diverse importance to human beings.The efficacy of microwave-assisted extraction (MAE) in the recovery of phenolic compounds from C.papaya leaf was investigated in this study.The MAE process variables were optimized sansamp rack using response surface method; at the optimized conditions, the embedded phenoli
In the era of mobile Internet, college students increasingly tend to express their opinions and views through online social media; furthermore, social media influence the value judgments of college students.Therefore, it is vital to understand and analyze university online public opinion over time.In this paper, we propose a data-driven architectur
Primordial germ cell (PGC) specification occurs early in development.PGC specifiers have been identified in Drosophila, mouse, and human but remained elusive in most animals.Here we identify the RNA-binding protein Dnd as a critical PGC specifier in the medaka fish (Oryzias latipes).Dnd depletion specifically abolished PGCs, and its overexpression